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The goal of this study was to determine if the sensitization induced by ET-1 priming is occurring at the level of the primary afferentneuron.
2
At the level of the primary afferentneuron, ET-1 priming has a desensitizing effect on challenge exposures to ET-1 and capsaicin.
3
The behavioral effects would be paralleled by changes in response properties of primary afferentneurons.
4
Afferentneurons in the DRGs that innervated the joints were identified using retrograde fluorogold labeling.
5
Substance P is a neuropeptide released by afferentneurons in the respiratory tract during inflammatory reactions.
Usage of sensory neuron in English
1
However, the contribution of target tissues to subsequent sensoryneuron development remains unknown.
2
The mechanisms by which sensoryneuron responses are altered on different timescales during adaptation are unclear.
3
Finally, sensoryneuron specific Rest knockout prevented injury-induced downregulation of REST target genes in DRG neurons.
4
Our results indicate that these markers largely characterize independent sets of olfactory sensoryneuron axons and glomeruli.
5
Pain-producing heat is detected by several classes of nociceptive sensoryneuron that differ in their thermal response thresholds.
6
Labeling of vomeronasal sensoryneuron axons in the accessory olfactory bulb was more uniform for the two lectins.
7
Positioned within the sensoryneuron, this source of current reconciles the physiology and anatomical characteristics of Atoh1 knockout animals.
8
This growth is associated with a down-regulation in the sensoryneuron of Aplysia cell adhesion molecules (apCAMs).
9
There is an increase and a decrease, respectively, in the number of sensoryneuron varicosities in response to 5-HT and FMRFamide.
10
Thus, at-HMGB1 activation through RAGE may be responsible for sensoryneuron sensitization and mechanical hyperalgesia associated with chronic neuropathic pain states.
11
Conspicuously, existing in vitro models aimed to decipher molecular mechanisms of mechanosensation test single sensoryneuron somata at any one time.
12
When physical strain is applied to the cuticle, CS external structures are compressed, leading to transduction in an internal sensoryneuron.
13
The capsaicin receptor, VR1, is a sensoryneuron-specific ion channel that serves as a polymodal detector of pain-producing chemical and physical stimuli.
14
Incubation of the rat sensoryneuron-derived cell line ND7 in serum-free medium results in the arrest of mitosis and the appearance of numerous neuronal processes.
15
Thus, using (S)-LCM to inhibit CRMP2 phosphorylation is a novel and efficient strategy to treat pain, which works by targeting specific sensoryneuron populations.
16
IL-31 was released by dermal conventional type 2 dendritic cells (cDC2s) recruited to wounds and increased itch sensoryneuron sensitivity.